Frey syndrome is characterized by unilateral flushing and sweating of the facial skin innervated by the auriculotemporal nerve (neck, parotid region, and. A neurologist from Poland, Dr. Lucja Frey, provided a detailed assessment of the disorder and coined the term “auriculotemporal syndrome” in Auriculotemporal nerve syndrome, also known as Frey syndrome, is an uncommon clinical entity in children. It is widely thought to be the result.

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Squamous cell papilloma Keratoacanthoma Malignant: The symptoms of Frey syndrome can include flushing, sweating, burning, neuralgia, and itching.

Auriculotemporal Syndrome (Frey Syndrome)

General Discussion Summary Frey syndrome is a rare disorder that most often occurs as a result of surgery in the area near the parotid glands. Auriculotemporal Syndrome Frey Syndrome. Another rarely described cause etiology of Frey syndrome is damage to the main sympathetic nerve chain in the neck.

Individuals are then given an oral stimulus usually a highly acidic food such as a lemon wedge. Sweat glands and blood vessels throughout the body are controlled by sympathetic fibers. Retrieved from ” https: Get free access to newly published articles Create a personal account or sign in to: Numerous products aruiculotemporal been reported, but the most commonly cited are acellular dermal matrix implantation and autologous fat grafting.

Food allergy is bilateral and presents with itching, urticaria, angioedema, or systemic symptoms or anaphylaxis. Box Bethesda, MD Phone: Sign in to customize your interests Sign in to your personal account.

Frey Syndrome – NORD (National Organization for Rare Disorders)

Otolaryngologic Clinics of Auriculotem;oral America49 2 Palate Bednar’s aphthae Cleft palate High-arched palate Palatal cysts of the newborn Inflammatory papillary hyperplasia Stomatitis nicotina Auriculotemporak palatinus.


This area is then coated with starch powder. Prevention of Frey syndrome has been guided by the alteration of surgical techniques or the addition of procedures focused on preventing synkinesis.

This page was last edited on 12 Decemberat Privacy Policy Terms of Use. Arch Otolaryngol Head Neck Surg.

Support Center Support Center. Please review our privacy policy. The sternocleidomastoid SCM muscles flap is auiculotemporal muscular flap with a tripartite blood supply. Increased Skin Flap Thickness Within the facial skin, the sweat glands are positioned at the same level or slightly deeper than the base of the hair follicles.

In affected individuals, discoloration usually purple due to excessive sweating occurs on the affected areas.

Treatment options include drug therapy or surgery. Surgical treatment for Frey syndrome refractory to medical management has been described, but clinical data to support its utilization are limited.

Articles needing additional references from December All articles needing additional references Infobox medical condition new All articles with unsourced statements Articles with unsourced statements from December The key symptom of facial syndroome is not emphasized in newborns rising doubts about the correctness of these observations.

Orofacial soft tissues — Soft tissues around the mouth Actinomycosis Angioedema Basal cell carcinoma Cutaneous sinus of dental origin Cystic hygroma Gnathophyma Ludwig’s angina Macrostomia Melkersson—Rosenthal syndrome Microstomia Noma Oral Crohn’s disease Orofacial granulomatosis Perioral dermatitis Pyostomatitis vegetans. Interposition of different barriers overlying the parotid to prevent aberrant reinnervation between parasympathetic and sympathetic fibers, has auricultemporal found to be useful.

Sign in to make a comment Sign in to your personal account. A recent meta-analysis concluded that the interposition of tissue after parotidectomy might decrease the incidence of Frey syndrome after parotidectomy.


General hyperhidrosis refers to any condition that causes excessive sweating hyperhidrosis on large areas of the body.

Frey syndrome was first described by Lucie Frey in and was termed auriculotemporal syndrome. In both patients there was a history of parotitis following abdominal surgery.

The exact underlying mechanisms that cause Frey syndrome are not fully understood. Spontaneous resolution has also been reported in children. Orofacial soft tissues — Soft tissues around the mouth. Link to publication in Scopus.

Frey’s syndrome

Many surgical techniques, which are aimed at creating a barrier between the transected parotid gland and the overlying skin, have been used with varying degrees of success to prevent the development of Frey syndrome. National Center for Biotechnology InformationU. For information about clinical trials conducted in Europe, contact: Currently, BTA is the most widely used agent for intradermal injection. Frey syndrome in children has a benign and nonprogressive course. Frey syndrome is due to the misdirected regenerative process of the auriculotemporal nerve.

In contrast to food allergy, Frey syndrome is usually unilateral, with a segmental distribution in the areas innervated by the auriculotemporal nerve.

The exact underlying cause of Frey syndrome is not completely understood. Normally, damaged nerve fiber s eventually heal themselves regenerate.

In very limited studies, there have been reports that abdominal fat implantation decreases the occurrence of Frey syndrome.

Topical application of drugs that block certain activities of the nervous system anticholinergics or drugs that hinder sweating antihidrotics have been used.

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