Identification of new genovariants of canine distemper virus in dogs from the State of el análisis del gen de la nucleocápside en perros del Estado de México.
|Published (Last):||3 July 2015|
|PDF File Size:||15.84 Mb|
|ePub File Size:||19.38 Mb|
|Price:||Free* [*Free Regsitration Required]|
The viral infection can be accompanied by secondary bacterial infections and can present eventual serious neurological symptoms. Molecular analysis of the N gene of canine distemper virus in dogs in Brazil.
petros A pair of primers previously reported by Shin et al was used to amplify a bp fragment of the N gene. A dog that survives distemper continues to have both nonlife-threatening and life-threatening signs throughout its lifespan.
It is caused by an RNA canine paramyxovirus with an elevated genetic diversity.
Comparison of amino acid sequences. A number of vaccines against canine distemper exist for dogs ATCvet code: J Vet Sci 2, These are some of the reasons why the N gene is a candidate for studies; also the sequences of this gene allow the differentiation among the strains of CDV Simon-Martinez et al Neurological signs typically are found in the animals with thickened footpads from the virus. Archived from the original on 18 January Canine distemper virus tends to orient its infection towards the lymphoidepithelialand nervous distempwr.
These infected cells have inclusions which stain a carmine red color, found in the paranuclear cytoplasm readability. Find a Veterinarian Near Aust Vet J 82, Currently, there are few studies focusing on the correlation of mutations in the N gene with changes in antigenicity and pathogenicity. In dogs, signs of distemper vary widely from no signs, to mild respiratory signs indistinguishable from kennel coughto severe pneumonia with vomiting, bloody diarrhea, and death.
However, several febrile diseases match many of the signs of the disease and only recently has distinguishing between canine hepatitisherpes virus, parainfluenzaand leptospirosis been possible.
These affected teeth tend to erode quickly. All but one infected panda died; the survivor had previously been vaccinated. Greene, Ian Tizard, et al. The virus contributed to the near-extinction of the black-footed ferret. Vet J Dog Disorders and Diseases: The virus first appears in bronchial lymph nodes and tonsils 2 days after exposure.
Distemper is caused by a single-stranded RNA virus of the family Paramyxoviridaewhich is a close relative of the viruses that cause measles in humans and rinderpest in animals. The multiple sequence alignment, molecular and phylogenetic analysis were realized using the MEGA 4.
This first round of fever typically recedes rapidly within 96 hours, and then a second round of fever begins around the 11th or 12th day and lasts at least a week. Examples include administering fluids, electrolyte solutions, analgesics, anticonvulsants, broad-spectrum antibiotics, antipyretics, parenteral nutrition, and nursing care. The domestic dog has largely been responsible for introducing canine distemper to previously unexposed wildlife, and now causes a serious conservation threat to many species of carnivores and some species of marsupials.
Molecular analysis of the nucleocapsid protein of recent isolates of canine distemper virus in Japan.
However, the disease continues to spread among unvaccinated rn, such as those in animal shelters and pet stores. Canine Distemper, see “Archived copy”.
Vet Microbiol 59, Canine Distemper terminal and intergenic non-protein coding nucleotide sequences: