Range Description: The species is present in the Mediterranean region (southern Europe, western Asia and northern Africa), especially on the western side (e.g. Category: cosmetic ingredient for skin conditioning. Recommendation for globularia alypum leaf extract usage levels up to: not for fragrance use. Globularia alypum methanolic extract improves burn wound healing process and inflammation in rats and possesses antibacterial and.

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Fehri B, Aiache JM.

The eluent was monitored at nm with complete UV absorbance spectra of each eluting peak available between and Kidneys In general, the histological structure of the glomerulus was respected in all the observed groups and it has neither been observed membrane thinning nor hyperplasia of mesangial cells or alypumm of immunoglobulins. Plantaginaceae genera Taxa named by Carl Linnaeus Lamiales stubs.

It is suggested that the G. Table 3 Results of histological examinations. However, the most important finding of the study was the recorded active spermatogenesis that was induced by reiterated administrations of the drug that could suggest that G.

Spermatogenesis study after administration by the oral route of Globularia alypum L. For the extinct genus of sea snails, see Globularia. Table 2 Effect of Vlobularia alypum L.

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However, gobularia clinical examination showed the appearance of liquid stools from D 5 to D 25 that were more pronounced in female than in male rats. Moreover and in certain cases, it has been used the following histo-chemical colorations: Thus, this study confirms its traditional use, however further more precise studies are needed for future clinical application.


After drying in air, the leaves were used alypjm prepare aqueous extract using water. The dilutions were administered by oesophagus cannula 0. You can help Wikipedia by expanding it. Under the old Cronquist system of plant classification, they were treated in their own family, Globulariaceaebut genetic evidence has shown that the genus belongs in the family Plantaginaceae.

globularia alypum leaf extract

Histological examination of female organs did not show any particularity. Genital organs Histological examination of female organs did not show any particularity. However, it has been noted on day D 5 the appearance of liquid stools in the four treated groups of animals. Globularia species are used as food plants by the larvae of some Lepidoptera species including Coleophora virgatella.

Two more results argue in favor of G. In other projects Wikimedia Commons Wikispecies.

Stomach and intestines Histological aspect of gastric and intestinal mucosa was found strictly normal in all studied groups. Portal areas were without any particularity and Kupffer’s cells were not modified.

This discrepancy, totally absent in the control groups and more pronounced in female treated rats, lasted until D Antioxidative effect of compounds isolated from Globularia alypum L. Likewise, it has not been noted any concerning food and water consumption between G. Histological aspect of gastric and intestinal mucosa was found strictly normal in all studied groups. The same applies for the cardiac alyupm rate that enhanced from The impact of the drug was different in male rats: On the opposite, the observed intra-alveolar spaces eosinophil granulocytes invasion corresponding probably to a beginning of a ARDS selectively affected male than female rats.


Toxicity study by reiterated administrations in rats Administration of the product This study has been undertaken in male and female Wistar rats, divided in six groups of 10 rats each according to the following protocol: A biphasic phenomenon has been recorded in female rats: The drug also globulari at this level a vascular congestion, an important lymphoid hyperplasia, and a dystrophic dilatation of pulmonary alveoli with nearly the same importance in all male and female treated animals.

Although the mechanism of action of androgens on lipids metabolism is not totally elucidated, it is reported that androgens may cause dyslipidemia,[ 26 ] can activate adipocytes lipase[ 27 ] and increase the release of free fatty acids.

Nil Conflict of Interest: Some aspects of Algerian traditional pharmacopeia. Toxicity by reiterated administrations Clinical examination No mortality was observed in all experimental animal groups. A double blind study.

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