Altoprev (lovastatina de liberación prolongada), Livalo (pitavastatina), Pravacol (pravastatina), Crestor (rosuvastatina) y Zocor (simvastatina). Al igual que otras estatinas, la pravastatina inhibe en forma competitiva a la La coadministración con fibratos (bezafibrato, gemfibrozilo), niacina, eritromicina. fluvastatina mg, lovastatina 40 mg, pravastatina. 40 mg . 3A4: ciclosporina, fibratos (gemfibrozil, bezafibrato, fenofibrato y ciprofibrato).

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Concomitant administration of cholestyramine influences the absorption of troglitazone. Effects of orlistat, a lipase inhibitor, on the pharmacokinetics of three highly lipophilic drugs amiodarone, fluoxetine, and simvastatin in healthy volunteers. Henao 1M. Antiplatelet effects of a mg loading dose of clopidogrel are not attenuated in patients receiving atorvastatin or simvastatin bezafibrwto at least 4 weeks prior to coronary artery stenting.

Drug interactions; Rhabdomyolisis; Hypolipidemic drugs. Ezetimibe-associated myopathy in monotherapy bezafibrao in combination with a 3-hydroxymethylglutaryl coenzyme A reductase inhibitor. A phase I, open-label, multiple-dose, three-period crossover study in healthy subjects.

Am J Cardiol ;96 suppl 9A: Plasma concentrations of active lovastatin acid are markedly increased by gemfibrozilo but not by bezafibrate. The effect of fluconazole on the pharmacokinetics of rosuvastatin. Grapefruit juice greatly increases serum concentrations of lovastatin and lovastatin acid. Gemfibrozil markedly increases the pravasgatina concentrations of montelukast: Drug Metabol Drug Interact.


Accumulation of lovastatin, but not pravastatin, in the blood of cyclosporine-treated kidney graft patients after multiple doses. Simvastatin-nelfinavir interaction implicated in rhabdomyolysis and death. Pharmacokinetic interaction between nelfinavir and pravastatin in HIV-seronegative volunteers: J Cardiovasc Pharmacol Ther.

The effect of the newly developed angiotensin receptor II antagonist fimasartan on the pharmacokinetics pravastwtina atorvastatin in relation to OATP1B1 in healthy male volunteers.

[De-sensitization to allopurinol in a patient with tophi gout].

Pharmacokinetics of rosuvastatin when coadministered with rifampicin in healthy males: Experience shows that de-sensitization to allopurinol is a safe alternative when there is hypersensitivity and treatment with this drug is required. Lack of pharmacokinetic interaction of colestipol and fenofibrate in volunteers. Absence of interactionbetween atorvastatin or other statins and clopidogrel: Platelet aggregation inhibition in patients receiving statins either fully or partially metabolized by CYP3A4.

Not all statins interfere with clopidogrel during antiplatelet therapy. Effect of atorvastatin on the pharmacokinetics and pharmacodynamics of prasugrel and clopidogrel in healthy subjects. Rhabdomyolysis secondary to a drug interaction between simvastatin and clarithromycin.

Se obtuvieron publicaciones, de las cuales se seleccionaron referencias, en las los que se identificaron interacciones. Br J Hosp Med Lond. Influence of statin treatment on platelet inhibition by clopidogrel-a randomized comparison of rosuvastatin, atorvastatin and simvastatin co-treatment.

Pravastatina: MedlinePlus medicinas

Rhabdomyolysis with atorvastatin and fusidic acid. Simvastatin does not have a clinically significant pharmacokinetic interaction with fenofibrate in humans. Basic Clin Pharmacol Toxicol. Rhabdomyolysis induced by rosuvastatin and sildenafil.



Enferm Infecc Microbiol Clin. Pharmacokinetic interactions between statins and fibrates. J Acquir Immune Defic Syndr. Effect of linagliptin BI on the steady-state pharmacokinetics of simvastatin. Simvastatin but not pravastatin is very susceptible to interaction with the CYP3A4 inhibitor itraconazole.

Tratamiento de la hipertrigliceridemia: The following Mesh terms were used: Enhanced cholesterol reduction by simvastatin in diltiazem-treated patients. Am J Health Syst Pharm. Irbesartan does not affect the pharmacokinetics of simvastatin in healthy subjects. Interacciones medicamentosas de mayor relevancia en hipolipemiantes.

Andreou ER, Ledger S. Por ello, las estatinas metabolizadas por la CYP3A4 como la simvastatina, lovastatina y atorvastatina son las estatinas que presentan mayor evidencia sobre las interacciones, mientras que la pravastatina posee un mejor perfil de seguridad debido a que no es metabolizado por CYP El alopurinol es un inhibidor de la xantinooxidasa usado en el tratamiento de pacientes con gota.

Rhabdomyolysis and acute renal failure induced by combination lovastatin and gemfibrozil therapy. J R Coll Physicians Edinb. Rhabdomyolysis following co-prescription of fusidic acid and atorvastatin.

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