The purpose of the study is to evaluate the physical performance of a Biograph mCT Flow R PET/CT system (Siemens Healthcare, Germany) and to. to fundamentally change how PET imaging is performed. Powered by Siemens’ revolutionary FlowMotion™ technology,. Biograph mCT Flow™ is the world’s first. Biograph mCT Flow with FlowMotion™ technology combines our standard- setting PET/CT with a unique system design that enables continuous motion of.

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No attenuation and scatter correction and no post-smoothing filter were applied.

Biograph mCT Flow – Siemens Healthineers USA

For the OSEM biogfaph, the biogrxph were slightly worse, which can be explained by the difference in applied post-filtering 3-mm FWHM vs 5-mm FWHM and the difference in iterations and subsets; the larger number of subsets in our study will lead to an enhancement of the noise in the image.

Furthermore, no relevant difference of the SUV mean of the liver as reference organ could be observed, and the comparison of the CVs of the liver showed no clinical relevant differences. Based on the results of Armstrong [ 25 ], this difference would increase for the smaller spheres when TOF was included into the reconstruction algorithm.

System true event rate, random event rate, scatter event rate, NECR, and the scatter fraction are reported.

This is the result of the low sensitivity in this part of the axial FOV Fig. The CRCs were similar in both acquisition modes. This difference warrants further discussion. In this study, the IQ phantom images were acquired with a table speed of 0. Also, advanced acquisition protocols like described by Karakatsanis et al. The CTM FlowMotion technology requires a new design of the patient table and the acquisition electronics.

Our data indicate a similar performance of the PET components of the mCT Flow and its predecessor system, the mCT [ 6 ] with the residual differences being discussed below.


The expected value of the true count rate ibograph gained by a fit through all data below the peak NECR standard as opposed to the extrapolated values from the last three acquisitions standard. Fully 3-D PET reconstruction with system matrix derived from point source measurements.

TOF information was not used in this measurement. The changes in bladder filling are caused by the time between biograoh scans.

No visual difference in overall PET image quality was biograpj by two experienced imaging experts. The acquisition electronics is based on solid-state components capable of continuously recording and biovraph detector addresses. Evaluation was done using in-house software.

No noticeable differences were seen in the contrast recovery as well as in the image quality obtained with sequential and CTM acquisition modes, although the background variability in the phantom measurements was slightly higher when using CTM acquisitions.

Biograph mCT 20 Excel

Data were reconstructed with an ordered-subset expectation maximization OSEM [ 25 ] 3D iterative algorithm, using 2 iterations i and 24 subsets sand additionally with 2 iterations and 21 subsets applying PSF correction and TOF.

For an axial FOV excluding the low sensitivity regions at the axial endpoints of the scan range a hypothetical scan with an unlimited number of bed positionsa 4-min acquisition per bed position corresponds to a table speed of 0.

The spatial resolution, sensitivity, scatter fraction, and count rates were in concordance with the published values for the predecessor system, the Biograph mCT.

The CTM acquisition followed the sequential subsequently.

A digital architecture for routinely storing and buffering the entire bit event stream at maximum bandwidth for every acquisition in clinical real-time 3-D PET: The clinically used settings of each system strongly depend on local on-site preferences. Image quality is very similar. These settings were selected to cover the same axial FOV in the same time as performed with the IQ phantom measurements. Image quality results for mft The reconstructions of the transaxial sections through the center of the spheres within the image quality phantom for SS and CTM mode are shown in Fig.


Resolution modeling in PET imaging: Open in a separate window. Footnotes Competing interests The authors declare that they have no competing interests. Furthermore, the axial placement of the off-center axial point sources was changed from one fourth of the axial FOV from the center to three eighth of the axial FOV from the center, biograoh.

National Electical Manufacturers Association. Dynamic whole body PET parametric imaging: The CTM scans were acquired with a table speed of 1. Traditionally, whole-body PET examinations are performed in step-and-shoot SS mode, introducing the patient table motion between consecutive acquisitions of adjacent bed positions [ 1011 ].

This configuration provides an axial field-of-view FOV of For the purpose of comparison between systems, this may not be sufficiently accurate. The bladder was chosen to test for this issue as it contains a uniform activity concentration and therefore similar to the background compartment in the IQ phantom.

All authors read and approved the final manuscript. Regarding the Biograoh test, the only difference between the and standard is a reduction of emission scan time by a factor of 2.

Biograph mCT Flow

We thank Alexander Biograpg Vienna for helping with the clinical comparison of the images. There were no visual differences in image quality of the patient scans Fig. Support Center Support Center. Please review our privacy policy. Nevertheless, contrast recoveries for both reconstructions were substantially lower biograpb the values published for the mCT system [ 6 ].

No noticeable difference between the two systems was observed. Performance measurements of positron emission tomographs. A second scan of the same region in CTM mode was acquired at a table speed of 0. The sphere-to-background ratio is 8:

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