Request PDF on ResearchGate | Intérêt des acides biliaires dans la cholestase gravidique | Intrahepatic cholestasis during pregnancy is a risk factor for. La cholestase gravidique a été reliée à des critères de jugement maternels et fœtaux/néonatals indésirables. Du fait que la physiopathologie est mal comprise, . Interventions pour le traitement de la cholestase gravidique. This is not the most recent version of this Review. view the current version 24 June

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Journal page Archives Contents list. Gracidique by the bile acid ursodeoxycholic acid improves pruritus and decreases the frequency of fetal complications, without side effects in the mother or baby. Access to the text HTML. Contact Help Who are we?

La cholestase gravidique Intrahepatic cholestasis of pregnancy. Access to the full text of this article requires a subscription.


Besides disturbing pruritus, maternal prognosis is good. Top of the page – Article Outline. As per the Law relating to information cnolestase and personal integrity, you have the right to oppose art 26 of that lawaccess art 34 of that law and rectify art 36 of that law your personal data. If you want to subscribe to this journal, see our rates You can purchase this item in Pay Per View: Personal information regarding our website’s visitors, including their identity, is confidential.


Access to the PDF text. Cholestasis of pregnancy presents with pruritus, sometimes incapacitating, less frequently by jaundice.

La cholestase gravidique – EM|consulte

You may thus request that your data, should it gravidlque inaccurate, incomplete, unclear, outdated, not be used or stored, be corrected, clarified, updated or deleted. In forms with severe pruritus, early delivery by induced labor between 37 and 38 weeks may be necessary.

Liver tests are abnormal, with mainly an increase in serum transaminases and bile acids. It graidique during the second or third trimester. Its prevalence in France is of the order of 1 per pregnancies. Elle survient pendant le 2 e ou le 3 e trimestre de la grravidique. It is slightly more frequent during twin pregnancies.

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Bile acids, Ursodeoxycholic acid, Prematurity, Pruritus. Outline Masquer le plan. If you are a subscriber, please sign in ‘My Account’ at the top right of the screen.



You can move this window by clicking on the headline. Clinical signs and biochemical abnormalities normalize rapidly after delivery, at most after 3 to 4 weeks. The disease is probably due to susceptibility to estrogens and progesterone, whose serum concentration is elevated during pregnancy and which are cholestatic.

Gravity of the disease comes from the occurrence of fetal complications, in particular prematurity often induced by obstetrical teams and its pulmonary complications, and dholestase intra-uterine fetal death. The susceptibility is explained by polymorphisms of genes encoding hepatocytic transport proteins that are important for bile secretion.

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